What does the lock and key hypothesis state?
By A Mystery Man Writer
Description
The key (substrate) fits perfectly in the lock (enzyme). The lock and key hypothesis states that the substrate fits perfectly into the enzyme, like a lock and a key would. This is in contrast with the induced fit hypothesis, which states that both the substrate and the enzyme will deform a little to take on a shape that allows the enzyme to bind the substrate. Since, the substrate binds to a specific enzyme, this hypothesis is meant for the substrate specific enzymes.
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